@inbook{aa2bd45cf37749159015610f3bf0754b,
title = "The Genetics and Cell Biology of Fertilization",
abstract = "Although the general events surrounding fertilization in many species are well described, the molecular underpinnings of fertilization are still poorly understood. Caenorhabditis elegans has emerged as a powerful model system for addressing the molecular and cell biological mechanism of fertilization. A primary advantage is the ability to isolate and propagate mutants that effect gametes and no other cells. This chapter provides conceptual guidelines for the identification, maintenance, and experimental approaches for the study fertility mutants.",
keywords = "Eggshell, Fertilization, Hermaphrodite, Oocyte, Oogenesis, Ovulation",
author = "Geldziler, {Brian D.} and Marcello, {Matthew R.} and Shakes, {Diane C.} and Andrew Singson",
note = "Funding Information: The authors thank Lisa Caiafa and members of the Singson Laboratory for helpful discussions, critical comments and advice. The authors also specifically wish to thank Pavan Kadandale, Indrani Chatterjee, and Rika Maruyama for assistance with figures, Penny Sadler for sharing unpublished spermatogenesis insights, and Alissa Richmond for immunostaining micrographs and unpublished sperm–oocyte fusion insights. The Singson Laboratory is supported by a grant from the NIH (R01 HD054681). The Shakes laboratory is supported by a grant from the NIH (R15 GM060359-02) to Diane C. Shakes. ",
year = "2011",
doi = "10.1016/B978-0-12-544172-8.00013-X",
language = "English (US)",
series = "Methods in Cell Biology",
publisher = "Academic Press Inc.",
pages = "343--375",
booktitle = "Methods in Cell Biology",
address = "United States",
}