Abstract
The HLA-A, -B, and -DR antigens were studied in black Americans to analyze deviation in phenotype distribution between ATS Class 3 patients with tuberculosis disease and ATS Class 2 healthy persons with significant tuberculin reaction, but no tuberculosis. Statistical analyses with Fisher's exact test revealed a significant difference in frequency distribution of HLA-B5 (p = 0.046), HLA-DR5 (p = 0.0276), and HLA-DR6y (p = 0.0095) between ATS Class 2 and ATS Class 3 patients. There was a significant decrease in HLA-DR6y (p = 0.01) but increase in HLA-B5 and HLA-DR5 phenotypes in ATS Class 3 patients.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 382-385 |
| Number of pages | 4 |
| Journal | American Review of Respiratory Disease |
| Volume | 132 |
| Issue number | 2 |
| State | Published - 1985 |
All Science Journal Classification (ASJC) codes
- Pulmonary and Respiratory Medicine