TY - JOUR
T1 - The importance of collagen fibers in vertebrate Biology
AU - Silver, Frederick H.
PY - 2009
Y1 - 2009
N2 - Collagen fibers form the basic structural components of extracellular matrix (ECM) of vertebrates that serve to: (1) store elastic energy during muscular deformation, (2) transmit stored energy into joint movement, and (3) transfer excess energy from the joint back to the attached muscles for dissipation. They also act as mechanotransducers by transferring stress borne by the musculoskeleton to the attached cells in order to either up - or down - regulate tissue metabolism as a result of changes in mechanical loading. Finally, they prevent premature mechanical failure of tissues by limiting deformation of most ECMs and organs.
AB - Collagen fibers form the basic structural components of extracellular matrix (ECM) of vertebrates that serve to: (1) store elastic energy during muscular deformation, (2) transmit stored energy into joint movement, and (3) transfer excess energy from the joint back to the attached muscles for dissipation. They also act as mechanotransducers by transferring stress borne by the musculoskeleton to the attached cells in order to either up - or down - regulate tissue metabolism as a result of changes in mechanical loading. Finally, they prevent premature mechanical failure of tissues by limiting deformation of most ECMs and organs.
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U2 - 10.1177/155892500900400203
DO - 10.1177/155892500900400203
M3 - Article
AN - SCOPUS:68249091677
SN - 1558-9250
VL - 4
SP - 9
EP - 17
JO - Journal of Engineered Fibers and Fabrics
JF - Journal of Engineered Fibers and Fabrics
IS - 2
ER -