The influence of PEG molecular weight on apparent hydrogel microsphere size as measured by the Coulter principle

Abhimanyu Cherukupalli, Michael Pellegrini, Ron Falkowski, Michael Medini, Ronke Olabisi

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Many researchers are currently investigating hydrogel microparticles for use in biomedical applications. Often, these investigations use the Coulter principle to evaluate the size distribution of their microparticles. Since this method uses the displacement of electrolyte to determine particle size, the electrolyte contained within the swelled hydrogel microparticles results in an underestimate of actual particle diameters. Using polyethylene glycol diacrylate (PEGDA) hydrogel microspheres, we attempted to determine a relation between polymer molecular weight and apparent Coulter diameter that would provide a correction for the underestimation.

Original languageEnglish (US)
Title of host publicationProceedings - 2014 40th Annual Northeast Bioengineering Conference, NEBEC 2014
PublisherInstitute of Electrical and Electronics Engineers Inc.
ISBN (Electronic)9781479937288
DOIs
StatePublished - Dec 2 2014
Event2014 40th Annual Northeast Bioengineering Conference, NEBEC 2014 - Boston, United States
Duration: Apr 25 2014Apr 27 2014

Publication series

NameProceedings of the IEEE Annual Northeast Bioengineering Conference, NEBEC
Volume2014-December
ISSN (Print)1071-121X
ISSN (Electronic)2160-7001

Other

Other2014 40th Annual Northeast Bioengineering Conference, NEBEC 2014
Country/TerritoryUnited States
CityBoston
Period4/25/144/27/14

All Science Journal Classification (ASJC) codes

  • Bioengineering

Keywords

  • Coulter principle
  • Hydrogels
  • Lypholization
  • Microspheres
  • PEGDA

Fingerprint

Dive into the research topics of 'The influence of PEG molecular weight on apparent hydrogel microsphere size as measured by the Coulter principle'. Together they form a unique fingerprint.

Cite this