TY - GEN
T1 - The investigation and clinical significance of resonance in the heart rate and vascular tone baroreflexes
AU - Vaschillo, Evgeny G.
AU - Vaschillo, Bronya
AU - Buckman, Jennifer F.
AU - Pandina, Robert J.
AU - Bates, Marsha E.
PY - 2011
Y1 - 2011
N2 - The heart rate (HR) and vascular tone (VT) baroreflexes are control systems with negative feedback. As closed-loop control systems with delays, they possess resonance features at approximately 0.1 Hz and 0.03 Hz, which correspond to a ∼5-s delay in the blood pressure (BP) response to HR changes and a ∼15-s delay in VT response to BP changes, respectively. Unlike a single impact on the cardiovascular system (CVS) that elicits HR, BP, and VT oscillatory responses that fade over time, rhythmical stimulation of the CVS at 0.1 Hz or 0.03-Hz produces steady HR, BP, and VT oscillations with significantly higher amplitudes compared to stimulation at other frequencies. We posit that these baroreflex resonances are integral to the vast autonomic variability that underlies efficient and effective homeostatic reflexes. This paper characterizes the phenomenon of resonances in the CVS using a classic engineering approach and the ability to employ these resonances for clinical applications.
AB - The heart rate (HR) and vascular tone (VT) baroreflexes are control systems with negative feedback. As closed-loop control systems with delays, they possess resonance features at approximately 0.1 Hz and 0.03 Hz, which correspond to a ∼5-s delay in the blood pressure (BP) response to HR changes and a ∼15-s delay in VT response to BP changes, respectively. Unlike a single impact on the cardiovascular system (CVS) that elicits HR, BP, and VT oscillatory responses that fade over time, rhythmical stimulation of the CVS at 0.1 Hz or 0.03-Hz produces steady HR, BP, and VT oscillations with significantly higher amplitudes compared to stimulation at other frequencies. We posit that these baroreflex resonances are integral to the vast autonomic variability that underlies efficient and effective homeostatic reflexes. This paper characterizes the phenomenon of resonances in the CVS using a classic engineering approach and the ability to employ these resonances for clinical applications.
KW - Baroreflex
KW - Closed-loop control system
KW - HRV biofeedback
KW - Resonance frequency
UR - http://www.scopus.com/inward/record.url?scp=79952525388&partnerID=8YFLogxK
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U2 - 10.1007/978-3-642-18472-7_18
DO - 10.1007/978-3-642-18472-7_18
M3 - Conference contribution
AN - SCOPUS:79952525388
SN - 9783642184710
T3 - Communications in Computer and Information Science
SP - 224
EP - 237
BT - Biomedical Engineering Systems and Technologies - Third International Joint Conference, BIOSTEC 2010, Revised Selected Papers
T2 - 3rd International Joint Conference on Biomedical Engineering Systems and Technologies, BIOSTEC 2010
Y2 - 20 January 2010 through 23 January 2010
ER -