The isolation of mutants of aspergillus flavus and A.parasiticus with altered aflatoxin producing ability

Joan Bennett, L. A. Goldblatt

Research output: Contribution to journalArticle

36 Citations (Scopus)

Abstract

Mutations affecting the production of aflatoxin might be useful in studying its biosynthesis, and in understanding the wide variation in aflatoxigenicity of fungal strains isolated from nature. Two methods of isolating mutants of Aspergillus in which aflatoxin production is attenuated or lost are presented. In one method mutants are selected on the basis of altered fluorescence under ultraviolet light. The second method utilizes a mutant strain which produces aflatoxin and an orange-red mycelial pigment not detected in the wild type. Unpigmented mutants derived from this strain exhibit lowered or lost aflatoxigenicity.

Original languageEnglish (US)
Pages (from-to)235-241
Number of pages7
JournalMedical mycology
Volume11
Issue number3
DOIs
StatePublished - Jan 1 1973

Fingerprint

Aspergillus flavus
Aflatoxins
aflatoxins
mutants
Aspergillus
Ultraviolet Rays
Fluorescence
ultraviolet radiation
Mutation
methodology
pigments
biosynthesis
fluorescence
mutation

All Science Journal Classification (ASJC) codes

  • Infectious Diseases

Cite this

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The isolation of mutants of aspergillus flavus and A.parasiticus with altered aflatoxin producing ability. / Bennett, Joan; Goldblatt, L. A.

In: Medical mycology, Vol. 11, No. 3, 01.01.1973, p. 235-241.

Research output: Contribution to journalArticle

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