The isolation of mutants of aspergillus flavus and A.parasiticus with altered aflatoxin producing ability

Joan W. Bennett, L. A. Goldblatt

Research output: Contribution to journalArticle

36 Scopus citations

Abstract

Mutations affecting the production of aflatoxin might be useful in studying its biosynthesis, and in understanding the wide variation in aflatoxigenicity of fungal strains isolated from nature. Two methods of isolating mutants of Aspergillus in which aflatoxin production is attenuated or lost are presented. In one method mutants are selected on the basis of altered fluorescence under ultraviolet light. The second method utilizes a mutant strain which produces aflatoxin and an orange-red mycelial pigment not detected in the wild type. Unpigmented mutants derived from this strain exhibit lowered or lost aflatoxigenicity.

Original languageEnglish (US)
Pages (from-to)235-241
Number of pages7
JournalMedical mycology
Volume11
Issue number3
DOIs
StatePublished - Jan 1 1973
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Infectious Diseases

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