The major role of Spo0A in genetic competence is to downregulate abrB, an essential competence gone

J. Hahn, M. Roggiani, D. Dubnau

Research output: Contribution to journalArticlepeer-review

65 Scopus citations

Abstract

We show that the major role for Spo0A in the development of genetic competence is to downregulate expression of abrB. AbrB is both a negative regulator and a positive regulator of competence. The negative effects are exerted at multiple points in competence regulation. A regulatory mechanism that is independent of mecA and abrB operates on comK expression.

Original languageEnglish (US)
Pages (from-to)3601-3605
Number of pages5
JournalJournal of bacteriology
Volume177
Issue number12
DOIs
StatePublished - 1995

All Science Journal Classification (ASJC) codes

  • Microbiology
  • Molecular Biology

Fingerprint

Dive into the research topics of 'The major role of Spo0A in genetic competence is to downregulate abrB, an essential competence gone'. Together they form a unique fingerprint.

Cite this