The mammalian Na+/H+ exchanger gene family - Initial structure/function studies

Ming Tse, Sue Levine, Chris Yun, Steve Brant, Jacques Pouyssegur, Mark Donowitz

Research output: Contribution to journalReview article

21 Scopus citations


A gene family of mammalian Na+/H+ exchangers has been identified. Three isoforms have been cloned, sequenced, and stably expressed, and structure/ function studies have been begun. Several of the Isoforms are found in the epithelia, and one of them is epithelial specific.

Original languageEnglish (US)
Pages (from-to)969-975
Number of pages7
JournalJournal of the American Society of Nephrology
Issue number4
StatePublished - Oct 1 1993
Externally publishedYes


All Science Journal Classification (ASJC) codes

  • Nephrology


  • Gene family
  • Na absorption
  • Transport protein

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