The migration of dna into a DNA-crosslinked gel using electrophoresis

David C. Lin, Noshir A. Langrana, Bernard Yurke

Research output: Contribution to journalConference articlepeer-review

1 Scopus citations

Abstract

DNA-crosslinked polyacrylamide gels are polymeric electrolytes by virtue of the fact that DNA is negatively charged in an aqueous solution. As such, their mechanical properties can be altered by electrophoretic and electro-osmotic effects. Hybridization of single-stranded DNA with single-stranded sections of the crosslinks provides a novel means of altering gel mechanical properties. As a step toward exploring this means of altering gel mechanical properties, we report here on a study of the use of electrophoresis to introduce single stranded DNA into DNA crosslinked gels. Changes in elastic properties of the gel, before and after electrophoresis, were measured.

Original languageEnglish (US)
Pages (from-to)131-132
Number of pages2
JournalAmerican Society of Mechanical Engineers, Bioengineering Division (Publication) BED
Volume55
DOIs
StatePublished - 2003
Event2003 ASME International Mechanical Engineering Congress - Washington, DC., United States
Duration: Nov 15 2003Nov 21 2003

All Science Journal Classification (ASJC) codes

  • Engineering(all)

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