DNA-crosslinked polyacrylamide gels are polymeric electrolytes by virtue of the fact that DNA is negatively charged in an aqueous solution. As such, their mechanical properties can be altered by electrophoretic and electro-osmotic effects. Hybridization of single-stranded DNA with single-stranded sections of the crosslinks provides a novel means of altering gel mechanical properties. As a step toward exploring this means of altering gel mechanical properties, we report here on a study of the use of electrophoresis to introduce single stranded DNA into DNA crosslinked gels. Changes in elastic properties of the gel, before and after electrophoresis, were measured.
|Original language||English (US)|
|Number of pages||2|
|Journal||American Society of Mechanical Engineers, Bioengineering Division (Publication) BED|
|State||Published - 2003|
|Event||2003 ASME International Mechanical Engineering Congress - Washington, DC., United States|
Duration: Nov 15 2003 → Nov 21 2003
All Science Journal Classification (ASJC) codes