@article{2ba632267b294df69d62fd06df483af3,
title = "The molecular organization of the Antennapedia locus of drosophila",
abstract = "The Antennapedia complex (ANT-C) of Drosophila is a cluster of genes involved in the regulation of morphogenesis, including at least three homoeotic loci (Antp, Scr, and pb), in which mutations cause switches of cell fates from one developmental pathway to another. We have isolated DNA clones containing most of the ANT-C, a region of about 300 kb. Antp mutations are distributed across more than 100 kb of the ANT-C. Dominant Antp mutations are associated with certain chromosome rearrangements and insertions that interrupt the 100 kb region; other chromosome breaks within the region cause recessive lethality and have no dominant effects. Two prominent transcripts (3.5 and 5.0 kb) are derived from exons within and at the two ends of the 100 kb region.",
author = "Scott, {Matthew P.} and Weiner, {Amy J.} and Hazelrigg, {Tulle I.} and Polisky, {Barry A.} and Vincenzo Pirrotta and Franco Scalenghe and Kaufman, {Thomas C.}",
note = "Funding Information: We thank Robert Laymon for excellent technical assistance. Drs. Welcome Bender, Michel Goldschmidt-Clermont, Robert Saint, and David Hcgness generously provided us with clones from the 67D region, cDNA libraries, and advice. Drs. Dietmar Mischke, Mary Lou Pardue, Bruce Baker, and Marianna Wolfner provided valuable unpublished information and clones from their chromosome walks in the @-tubulin gene region, We thank Drs. Robert Boswell and Edwin Stephenson for help and materials, Dr. Jose Bonner for the use of facilities, and Mary Anne Puftz for clones A615 and A589. We are grateful to Drs. Barbara Wakimoto, Welcome Bender, Michael Akam, and fgor Dawid for valuable discussions and unpublished data: to Drs. Chao Ting Wu, Gary Struhl, Ian Duncan, and Ed Lewis for mutants; and to Dr. Tom Blumenthal and Mark Mortin for reviewing the manuscript. Brian Foster, Tim Fitzwater, and Helen Arthur helped in many ways. M. P. S. was supported by a fellowship from the Helen Hay Whitney Foundation. 8. A. P. was supported by a Research Career Development Award from the National Institutes of Health. The research was funded by a National Institutes of Health grant to T. C. K.",
year = "1983",
month = dec,
doi = "10.1016/0092-8674(83)90109-5",
language = "English (US)",
volume = "35",
pages = "763--776",
journal = "Cell",
issn = "0092-8674",
publisher = "Cell Press",
number = "3 PART 2",
}