The muir-torre syndrome: A disease of sebaceous and colonic neoplasms

Robert A. Schwartz, David J. Goldberg, Fayyaz Mahmood, Robert L. De Jager, W. Clark Lambert, Ahmad Z. Najem, Philip J. Cohen

Research output: Contribution to journalArticlepeer-review

39 Scopus citations


The Muir-Torre syndrome of sebaceous neoplasms of the skin, with or without keratoacanthomas, and multiple low-grade visceral malignancies with prolonged survival is a rare disorder. Colonic polyps are frequently present, and the syndrome appears to be familial. We report 2 unrelated patients with the Muir-Torre syndrome. Each case exhibited sebaceous adenomas. Gastrointestinal findings included colonic adenocarcinomas and a tubulovillous adenoma. Although an unusual disease, the Muir-Torre syndrome requires recognition because these patients are at risk for multiple primary malignancies and may have family members also at risk.

Original languageEnglish (US)
Pages (from-to)23-28
Number of pages6
Issue number1
StatePublished - 1989

All Science Journal Classification (ASJC) codes

  • Dermatology


  • Cancer family syndrome
  • Gastrointestinal malignancies
  • Muir-Torre syndrome
  • Sebaceous adenoma
  • Sebaceous neoplasms
  • Sebaceous tumors
  • Torre syndrome
  • Torre-Muir syndrome
  • Tubulovillous adenoma
  • Visceral malignancies


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