The retron: a bacterial retroelement required for the synthesis of msDNA

Sumiko Inouye, Masayori Inouye

Research output: Contribution to journalArticlepeer-review

27 Scopus citations

Abstract

'Retrons' are bacterial retroelements responsible for the synthesis of msDNA, a hybrid nucleic acid consisting of a single-stranded DNA that is branched out from an internal guanosine of an RNA molecule via a 2′,5′-phosphodiester linkage. Retrons are found in a minor population of various bacterial species and are extensively diverse. Two important questions now demanding attention are whether retrons are mobile elements and why are they so diverse?

Original languageEnglish (US)
Pages (from-to)713-718
Number of pages6
JournalCurrent Opinion in Genetics and Development
Volume3
Issue number5
DOIs
StatePublished - Oct 1993

All Science Journal Classification (ASJC) codes

  • Genetics
  • Developmental Biology

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