Abstract
Glioblastoma multiforme is a malignant primary brain tumor for which no cure has been developed. However, with aggressive surgical resection, radiation, and the advent of temozolomide, the overall survival of patients with glioblastomas has improved significantly. Despite this multimodal treatment, glioblastoma invariably recurs. Although treatment options for glioblastoma recurrence are limited, one promising therapy is bevacizumab (Avastin). The role of Avastin in the management of recurrent glioblastomas is reviewed.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 331-341 |
| Number of pages | 11 |
| Journal | Neurosurgery clinics of North America |
| Volume | 23 |
| Issue number | 2 |
| DOIs | |
| State | Published - Apr 2012 |
| Externally published | Yes |
All Science Journal Classification (ASJC) codes
- Surgery
- Clinical Neurology
Keywords
- Angiogenesis
- Angiogenic switch
- Antiangiogenic
- Avastin
- Bevacizumab
- Radiation necrosis
- Recurrent glioblastoma
- Treatment malignant glioma
- VEGF
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