The role of Eph receptors in lens function and disease

Alexander I. Son, Jeong Eun Park, Ren Ping Zhou

Research output: Contribution to journalReview article

11 Scopus citations

Abstract

Cataract is the single largest contributor to blindness in the world, with the disease having a strong genetic component. In recent years the Eph family of receptor tyrosine kinases has been identified as a key regulator in lens clarity. In this review we discuss the roles of the Eph receptors in lens biology and cataract development.

Original languageEnglish (US)
Pages (from-to)434-444
Number of pages11
JournalScience China Life Sciences
Volume55
Issue number5
DOIs
StatePublished - May 2012

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All Science Journal Classification (ASJC) codes

  • Biochemistry, Genetics and Molecular Biology(all)
  • Environmental Science(all)
  • Agricultural and Biological Sciences(all)

Keywords

  • EphA2
  • cataract
  • ephrin-A5
  • lens

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