The status of LTP as a mechanism of memory formation in the mammalian brain

Research output: Contribution to journalShort surveypeer-review

Abstract

Long-term potentiation (LTP) is a long-lasting increase in synaptic efficacy that many consider the best candidate currently available for a neural mechanism of memory formation and/or storage in the mammalian brain. In our target article, LTP: What's learning got to do with it?, we concluded that there was insufficient data to warrant such a conclusion. In their commentaries, Jeffery and Zhadin raise a number of important issues that we did not raise, both for and against the hypothesis. Although we agree with a number of these issues, we maintain that there remains insufficient evidence that LTP is a memory mechanism.

Original languageEnglish (US)
Pages (from-to)288-291
Number of pages4
JournalBehavioral and Brain Sciences
Volume23
Issue number2
DOIs
StatePublished - Aug 9 2000

All Science Journal Classification (ASJC) codes

  • Neuropsychology and Physiological Psychology
  • Physiology
  • Behavioral Neuroscience

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