TY - JOUR
T1 - The structural and functional organization of intramolecular chaperones
T2 - The N-terminal propeptides which mediate protein folding
AU - Shinde, Ujwal
AU - Inouye, Masayori
PY - 1994/1/1
Y1 - 1994/1/1
N2 - A large number of prokaryotic as well as eukaryotic proteins are produced with amino terminal propeptides. These amino-terminal extensions are essential for mediating proper folding of their corresponding proteins and are also termed as intramolecular chaperones. Though these propeptides are highly specific and unique in their function, several common features have been identified and indicate that the overall mechanism by which they function may be very similar.
AB - A large number of prokaryotic as well as eukaryotic proteins are produced with amino terminal propeptides. These amino-terminal extensions are essential for mediating proper folding of their corresponding proteins and are also termed as intramolecular chaperones. Though these propeptides are highly specific and unique in their function, several common features have been identified and indicate that the overall mechanism by which they function may be very similar.
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U2 - 10.1093/oxfordjournals.jbchem.a124386
DO - 10.1093/oxfordjournals.jbchem.a124386
M3 - Review article
C2 - 7916340
AN - SCOPUS:0028223248
VL - 115
SP - 629
EP - 636
JO - Journal of Biochemistry
JF - Journal of Biochemistry
SN - 0021-924X
IS - 4
ER -