The use of multiparameter flow cytometry in immunotoxicology and immunopharmacology

Leigh Ann Burns-Naas; Nancy I. Kerkvliet; Debra L. Laskin; Carl D. Bortner; Scott W. Burchiel

The use of multiparameter flow cytometry in immunotoxicology and immunopharmacology

Leigh Ann Burns-Naas, Nancy I. Kerkvliet, Debra L. Laskin, Carl D. Bortner, Scott W. Burchiel

Ernest Mario School of Pharmacy, Pharmacology & Toxicology

Research output: Chapter in Book/Report/Conference proceeding › Chapter

2 Scopus citations

Abstract

The continual development and evolution of novel and powerful technologies has allowed scientists to answer increasingly complex questions about the basic mechanisms underlying cellular homeostasis for the benefit of human health. Our understanding of how cells proliferate, thrive, adapt, and die in response to numerous environmental conditions are at the heart of the fields of pharmacology and toxicology. The study of fluorescently labeled cells allows for an extension of our understanding of the consequences of various compounds on both the life and death of a cell. As such, flow cytometry has become a valuable technique for the study of toxicological effects as they relate to human health.

Original language	English (US)
Title of host publication	Immunotoxicology and Immunopharmacology, Third Edition
Publisher	CRC Press
Pages	97-122
Number of pages	26
ISBN (Electronic)	9781420005448
ISBN (Print)	9780849337901
State	Published - Jan 1 2006

All Science Journal Classification (ASJC) codes

Medicine(all)
Immunology and Microbiology(all)

Cite this

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title = "The use of multiparameter flow cytometry in immunotoxicology and immunopharmacology",

abstract = "The continual development and evolution of novel and powerful technologies has allowed scientists to answer increasingly complex questions about the basic mechanisms underlying cellular homeostasis for the benefit of human health. Our understanding of how cells proliferate, thrive, adapt, and die in response to numerous environmental conditions are at the heart of the fields of pharmacology and toxicology. The study of fluorescently labeled cells allows for an extension of our understanding of the consequences of various compounds on both the life and death of a cell. As such, flow cytometry has become a valuable technique for the study of toxicological effects as they relate to human health.",

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AU - Laskin, Debra L.

AU - Bortner, Carl D.

AU - Burchiel, Scott W.

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AB - The continual development and evolution of novel and powerful technologies has allowed scientists to answer increasingly complex questions about the basic mechanisms underlying cellular homeostasis for the benefit of human health. Our understanding of how cells proliferate, thrive, adapt, and die in response to numerous environmental conditions are at the heart of the fields of pharmacology and toxicology. The study of fluorescently labeled cells allows for an extension of our understanding of the consequences of various compounds on both the life and death of a cell. As such, flow cytometry has become a valuable technique for the study of toxicological effects as they relate to human health.

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ER -

The use of multiparameter flow cytometry in immunotoxicology and immunopharmacology

Abstract

All Science Journal Classification (ASJC) codes

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