The Use of Pharmacoepidemiology to Study Beneficial Drug Effects

Brian L. Strom, Kenneth L. Melmon

Research output: Chapter in Book/Report/Conference proceedingChapter

6 Scopus citations


In order to be approved for marketing in the United States, drugs must be proven to be safe and effective using "adequate and well-controlled investigations." This chapter clarifies the different definitions of various types of beneficial drug effects and discusses the need for postmarketing studies of drug effectiveness. Unique methodologic problems raised by studies of beneficial drug effects, and potential solutions to these problems, are also discussed. Finally, specific examples of approaches to the study of efficacy are presented.

Original languageEnglish (US)
Title of host publicationPharmacoepidemiology, Fifth Edition
Number of pages23
ISBN (Print)0470654759, 9780470654750
StatePublished - Jan 3 2012
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Medicine(all)
  • Pharmacology, Toxicology and Pharmaceutics(all)


  • Beneficial drug effect
  • Confounding by indication
  • Drug effect
  • Effectiveness
  • Efficacy
  • Non-experimental study
  • Observational study
  • Postmarketing study
  • Premarketing study


Dive into the research topics of 'The Use of Pharmacoepidemiology to Study Beneficial Drug Effects'. Together they form a unique fingerprint.

Cite this