The Use of Pharmacoepidemiology to Study Beneficial Drug Effects

Brian L. Strom; Kenneth L. Melmon

doi:10.1002/9781119959946.ch37

The Use of Pharmacoepidemiology to Study Beneficial Drug Effects

Brian L. Strom, Kenneth L. Melmon

Research output: Chapter in Book/Report/Conference proceeding › Chapter

6 Scopus citations

Abstract

In order to be approved for marketing in the United States, drugs must be proven to be safe and effective using "adequate and well-controlled investigations." This chapter clarifies the different definitions of various types of beneficial drug effects and discusses the need for postmarketing studies of drug effectiveness. Unique methodologic problems raised by studies of beneficial drug effects, and potential solutions to these problems, are also discussed. Finally, specific examples of approaches to the study of efficacy are presented.

Original language	English (US)
Title of host publication	Pharmacoepidemiology, Fifth Edition
Publisher	Wiley-Blackwell
Pages	655-677
Number of pages	23
ISBN (Print)	0470654759, 9780470654750
DOIs	https://doi.org/10.1002/9781119959946.ch37
State	Published - Jan 3 2012
Externally published	Yes

All Science Journal Classification (ASJC) codes

General Medicine
Pharmacology, Toxicology and Pharmaceutics(all)

Keywords

Beneficial drug effect
Confounding by indication
Drug effect
Effectiveness
Efficacy
Non-experimental study
Observational study
Postmarketing study
Premarketing study

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10.1002/9781119959946.ch37

Cite this

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BT - Pharmacoepidemiology, Fifth Edition

PB - Wiley-Blackwell

ER -

The Use of Pharmacoepidemiology to Study Beneficial Drug Effects

Abstract

All Science Journal Classification (ASJC) codes

Keywords

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