The purpose of this web-based study was to explain and predict consumers' acceptance and usage behavior of Internet health information and services. Toward this goal, the Information and Communication Technology Acceptance Model (ICTAM) was developed and tested. Individuals who received a flyer through the LISTSERV of HealthGuide were eligible to participate. The study population was eighteen years old and older who had used Internet health information and services for a minimum of 6 months. For the analyses, SPSS (version 13.0) and AMOS (version 5.0) were employed. More than half of the respondents were women (n=110, 55%). The average age of the respondents was 35.16 years (S.D.=10.07). A majority reported at least some college education (n=126, 63%). All of the observed factors accounted for 75.53% of the total variance explained. The fit indices of the structural model were within an acceptable range: χ2/df=2.38 (χ2=1786.31, df=752); GFI=.71; RMSEA=.08; CFI=.86; NFI=.78. The results of this study provide empirical support for the continued development of ICTAM in the area of health consumers' information and communication technology acceptance.