Thiamine triphosphatase in the nervous system

Robert L. Barchi, Peter E. Braun

Research output: Contribution to journalArticlepeer-review

4 Scopus citations


Thiamine triphosphate is hydrolyzed by a specific triphosphatase in subcellular fractions of rat brain. This enzyme differs from nucleoside triphosphatases in (1) its subcellular distribution pattern; (2) its susceptibility to inhibition by Ca2+; (3) its activation by sodium deoxycholate; (4) its failure to be affected by known inhibitors of other triphosphatases. The specific activity of the thiamine triphosphatase is as high as that of Mg2+-activated ATPase.

Original languageEnglish (US)
Pages (from-to)402-405
Number of pages4
JournalBBA - Biomembranes
Issue number1
StatePublished - Jan 17 1972
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Biophysics
  • Biochemistry
  • Cell Biology


Dive into the research topics of 'Thiamine triphosphatase in the nervous system'. Together they form a unique fingerprint.

Cite this