Thin film elastic modulus of degradable tyrosine-derived polycarbonate biomaterials and their blends

Khaled A. Aamer, Christopher M. Stafford, Lee J. Richter, Joachim Kohn, Matthew L. Becker

Research output: Contribution to journalArticlepeer-review

15 Scopus citations

Abstract

The integrity, function, and performance of biomedical devices having thin polymeric coatings are critically dependent on the mechanical properties of the film, including the elastic modulus. In this report, the elastic moduli of several tyrosine-derived polycarbonate thin films, specifically desaminotyrosyl ethyl tyrosine polycarbonates p(DTE carbonate), an iodinated derivative p(I2-DTE carbonate), and several discrete blends are measured using a method based on surface wrinkling. The data shows that the elastic modulus does not vary significantly with the blend composition as the weight percentage of p(I2-DTE carbonate) increases for films of uniform thickness in the range of 67 to 200 nm. As a function of film thickness, the observed elastic moduli of p(DTE carbonate), p(I2-DTE carbonate) and their 50:50 by mass blend show little variation over the range 30 to 200 nm.

Original languageEnglish (US)
Pages (from-to)1212-1218
Number of pages7
JournalMacromolecules
Volume42
Issue number4
DOIs
StatePublished - Feb 24 2009

All Science Journal Classification (ASJC) codes

  • Organic Chemistry
  • Polymers and Plastics
  • Inorganic Chemistry
  • Materials Chemistry

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