Three-dimensional motion reconstruction and analysis of the right ventricle using tagged MRI

I. Haber, Dimitris N. Metaxas, Leon Axel

Research output: Contribution to journalArticlepeer-review

85 Scopus citations

Abstract

Right ventricular (RV) dysfunction can serve as an indicator of heart and lung disease and can adversely affect the left ventricle. However, normal RV function must he characterized before abnormal states can be detected. We describe a method for reconstructing the 3D motion of the RV by fitting a deformable model to tag and contour data extracted from multiview tagged magnetic resonance images. The deformable model is a biventricular finite element mesh built directly from segmented contours. Our approach accommodates the geometrically complex RV by using the entire lengths of the tags, localized degrees of freedom, and finite elements for geometric modeling. Also, we outline methods for converting the 3D motion reconstruction results into potentially useful motion variables, such as strains and displacements. The technique was applied to synthetic data, two normal hearts, and two hearts with right ventricular hypertrophy (RVH). Noticeable differences were found between the motion variables calculated for normal volunteers and RVII patients.

Original languageEnglish (US)
Pages (from-to)335-355
Number of pages21
JournalMedical Image Analysis
Volume4
Issue number4
DOIs
StatePublished - 2000

All Science Journal Classification (ASJC) codes

  • Radiological and Ultrasound Technology
  • Radiology Nuclear Medicine and imaging
  • Computer Vision and Pattern Recognition
  • Health Informatics
  • Computer Graphics and Computer-Aided Design

Keywords

  • 3D motion
  • Deformable modeling
  • MRI tagging
  • Right ventricle

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