Thymolipoma: clues to pathogenesis revealed by cytogenetics

Rachel Hudacko, Hana Aviv, John Langenfeld, Billie Fyfe

Research output: Contribution to journalArticle

8 Scopus citations

Abstract

The pathogenesis of thymolipoma is controversial and unclear despite numerous reports. A case report of thymolipoma with cytogenetic analysis is herein presented. The lesion demonstrated a translocation involving the HMGA2 gene on chromosome 12q15, which is seen in two thirds of solitary lipomas. This finding supports the theory that this case of thymolipoma is a neoplasm of thymic fat.

Original languageEnglish (US)
Pages (from-to)185-188
Number of pages4
JournalAnnals of Diagnostic Pathology
Volume13
Issue number3
DOIs
StatePublished - Jun 1 2009

All Science Journal Classification (ASJC) codes

  • Pathology and Forensic Medicine

Keywords

  • HMGA2 gene
  • Lipoma
  • Thymolipoma
  • Thymus

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