Timing of copper intrauterine device insertion after medical abortion: A randomized controlled trial

Noa'A Shimoni, Anne Davis, Maria Elena Ramos, Linette Rosario, Carolyn Westhoff

Research output: Contribution to journalArticlepeer-review

45 Scopus citations


Objective: To compare intrauterine device (IUD) use at 6 months in women randomized to receive an intrauterine copper contraceptive 1 week compared with 1 month after medical abortion. Methods: We recruited women undergoing medical abortion with mifepristone and misoprostol and choosing the copper IUD for contraception. We randomly assigned participants to "immediate" insertion 1 week after mifepristone or "delayed" insertion 4-6 weeks later. We followed rates of IUD insertion, 6-month utilization, expulsion, removal, and pregnancy. Participants recorded bleeding in a diary for 4 weeks. Results: We randomized 156 participants. We inserted an IUD in 97% of participants in the immediate group and 76% in the delayed group (P<.001). At 6 months, 69% of participants in the immediate group used the IUD compared with 60% in the delayed group (P=.24). Expulsion rates were comparable; 12% (8 of 69) in the immediate group compared with 11% (7 of 65) in the delayed group. Removals occurred in 14% (10 of 69) of immediate and 8% (5 of 65) of delayed group participants (P=.21). Four pregnancies occurred in delayed group participants who did not return for IUD insertion (P=.09). The immediate and delayed groups reported a median of 20 and 19 bleeding or spotting days, respectively (P=.15). We detected no cases of serious infection, uterine perforation, or hemorrhage. Conclusion: Immediate insertion increased uptake of the IUD without increasing expulsions or bleeding.

Original languageEnglish (US)
Pages (from-to)623-628
Number of pages6
JournalObstetrics and gynecology
Issue number3
StatePublished - Sep 2011
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Obstetrics and Gynecology


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