TOLAZOLINE AND DOPAMINE THERAPY IN NEONATAL HYPOXIA AND PULMONARY VASOSPASM

THOMAS HEGYI, I. MARK HIATT

Research output: Contribution to journalArticlepeer-review

11 Scopus citations

Abstract

Abstract. Hegyi, T. and Hiatt, I. M. (Division of Perinatology, Monmouth Medical Center and Department of Pediatrics, the Hahnemann Medical College, Philadelphia, USA). Tolazoline and dopamine therapy in neonatal hypoxia and pulmonary vasospasm. Acta Paediatr Scand, 69: 101, 1980.—Severe hypoxia unresponsive to maximum ventilatory support occurs both in idiopathic respiratory distress syndrome and meconium aspiration. We recently encountered a 980 g female infant with respiratory distress syndrome and 3300 g female infant with meconium aspiration and persistant fetal circulation whose clinical course necessitated the use of tolazoline and dopamine to reduce pulmonary and to stabilize systemic pressures. The infant with respiratory distress syndrome responded with a PaO2 increase of 2.7 kPa while the infant with persistant fetal circulation and meconium aspiration showed a 51.6 kPa rise. Combined pharmacologic therapy may have a role in improving oxygenation status in severely hypoxemic infants receiving maximum support

Original languageEnglish (US)
Pages (from-to)101-103
Number of pages3
JournalActa Pædiatrica
Volume69
Issue number1
DOIs
StatePublished - Jan 1980
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Pediatrics, Perinatology, and Child Health

Keywords

  • dopamine
  • hypoxia
  • meconium aspiration syndrome
  • olazoline
  • respiratory distress syndrome

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