TY - JOUR
T1 - Trace metals in a family with sex-linked retinitis pigmentosa.
AU - Bastek, J.
AU - Bogden, J.
AU - Cinotti, A.
AU - TenHove, W.
AU - Stephens, G.
AU - Markopoulos, M.
AU - Charles, J.
PY - 1977
Y1 - 1977
N2 - Lead, cadmium, copper, and zinc levels were examined in RP patients, carriers, and controls in a family with sex-linked RP. The mean plasma copper concentration was significantly higher in the RP patients and carriers than in the controls. The mean plasma zinc concentration was significantly higher in the carriers than in the RP victims or controls. The mean plasma zinc/copper ratio was significantly lower in the RP victims than in the controls or carriers. These findings may help explain the onset of RP in some sex-linked carriers and may be of diagnostic value.
AB - Lead, cadmium, copper, and zinc levels were examined in RP patients, carriers, and controls in a family with sex-linked RP. The mean plasma copper concentration was significantly higher in the RP patients and carriers than in the controls. The mean plasma zinc concentration was significantly higher in the carriers than in the RP victims or controls. The mean plasma zinc/copper ratio was significantly lower in the RP victims than in the controls or carriers. These findings may help explain the onset of RP in some sex-linked carriers and may be of diagnostic value.
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U2 - 10.1007/978-1-4899-5010-9_6
DO - 10.1007/978-1-4899-5010-9_6
M3 - Article
C2 - 848399
AN - SCOPUS:0017429385
SN - 0065-2598
VL - 77
SP - 43
EP - 50
JO - Advances in experimental medicine and biology
JF - Advances in experimental medicine and biology
ER -