@inproceedings{0782207eb76648ad8c37af5496fd4837,
title = "Tracheal anastomosis using indocyanine green dye enhanced fibrinogen with a near-infrared diode laser",
abstract = "A major obstacle to lung transplantation and combined heart-lung transplantation is dehiscence of the tracheobronchial anastomosis. We explored the possibility of laser welded anastomoses in canine tracheas in vivo. Laser anastomoses were performed on three-quarter circumferential anterior tracheotomies. A continuous wave diode laser (808 ±1 nm) at a power density of 9.6 watts/cm2 was used. Human fibrinogen was mixed with indocyanine green dye (ICG, max absorbance 805 nm) and applied to the anastomosis site prior to laser exposure. Animals were sacrificed at 0, 21 and 28 days post-operatively. At sacrifice weld bursting pressures were measured by raising intratracheal pressure using forced ventilation via an endotracheal tube. Sutured and laser welded anastomoses had similar bursting pressures, and exhibited satisfactory histologic evidence of healing. However, compared to polypropylene sutured controls, the laser welded anastomoses exhibited less peritracheal inflammatory reaction and showed visibly smoother luminal surfaces at 21 and 28 days post-operatively. Tracheal anastomosis using ICG dye enhanced fibrinogen combined with the near-infrared diode laser is a promising extension of the technology of laser tissue fusion and deserves further study.",
author = "Auteri, {Joseph S.} and Valluvan Jeevanandam and Oz, {Mehmet C.} and Libutti, {Steven K.} and Kirby, {Thomas J.} and Smith, {Craig R.} and Treat, {Michael R.}",
year = "1990",
doi = "10.1117/12.17431",
language = "English (US)",
isbn = "0819402419",
series = "Proceedings of SPIE - The International Society for Optical Engineering",
publisher = "Publ by Int Soc for Optical Engineering",
pages = "60--63",
booktitle = "Proceedings of SPIE - The International Society for Optical Engineering",
note = "Proceedings of Laser Surgery: Advanced Characterization Therapeutics, and Systems II ; Conference date: 14-01-1990 Through 19-01-1990",
}