Transcription and mRNA stability: Parental guidance suggested

Vivian Bellofatto, Jeffrey Wilusz

Research output: Contribution to journalShort surveypeer-review

10 Scopus citations

Abstract

The level of an mRNA within a cell depends on both its rate of synthesis and rate of decay. Now, independent studies by Bregman et al. and Trcek et al. provide evidence that these two processes are integrated. They show that transcription factors and DNA promoters can directly influence the relative stability of transcripts that they produce.

Original languageEnglish (US)
Pages (from-to)1438-1439
Number of pages2
JournalCell
Volume147
Issue number7
DOIs
StatePublished - Dec 23 2011

All Science Journal Classification (ASJC) codes

  • Biochemistry, Genetics and Molecular Biology(all)

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