Transcription of novel open reading frames of AIDS retrovirus during infection of lymphocytes

Arnold B. Rabson, Daryl F. Daugherty, Sundararajan Venkatesan, Kim E. Boulukos, Steven I. Benn, Thomas M. Folks, Paul Feorino, Malcolm A. Martin

Research output: Contribution to journalArticlepeer-review

36 Scopus citations

Abstract

The retrovirus frequently isolated from patients with the acquired immune deficiency syndrome (AIDS) has two novel open reading frames previously designated "A" and "B." The "A" region was found to be specifically expressed as polyadenylated RNA's of 5.5 and 5.0 kilobases in infected cells. The "B" region was expressed as 1.8- to 2.0-kilobase RNA species. Additional full-length and spliced messenger RNA's of the env region were also identified.

Original languageEnglish (US)
Pages (from-to)1388-1390
Number of pages3
JournalScience
Volume229
Issue number4720
DOIs
StatePublished - 1985
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • General

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