Transcription: Why are TAFs essential?

Michael Hampsey, Danny Reinberg

Research output: Contribution to journalReview articlepeer-review

16 Scopus citations


The TAFs are transcription factors associated with the TATA-binding protein, and until recently they were assumed to link specific activators to the general transcription machinery. Recent results suggest that the essential functions of TAFs are not as coactivators of transcription but as determinants of promoter selectivity.

Original languageEnglish (US)
Pages (from-to)R44-R46
JournalCurrent Biology
Issue number1
StatePublished - Jan 1997

All Science Journal Classification (ASJC) codes

  • Biochemistry, Genetics and Molecular Biology(all)
  • Agricultural and Biological Sciences(all)

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