Abstract
Transforming growth factor-β is a pleiotropic growth factor that has enthralled many investigators for approximately two decades. In addition to many reports that have clarified the basic mechanism of transforming growth factor-β signal transduction, numerous laboratories have published on the clinical implication/application of transforming growth factor-β. To name a few, dysregulation of transforming growth factor-β signaling plays a role in carcinogenesis, autoimmunity, angiogenesis, and wound healing. In this report, we will review these clinical implications of transforming growth factor-β.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 1-8 |
| Number of pages | 8 |
| Journal | Journal of Biochemistry and Molecular Biology |
| Volume | 38 |
| Issue number | 1 |
| State | Published - 2005 |
| Externally published | Yes |
All Science Journal Classification (ASJC) codes
- Biochemistry
- Molecular Biology
Keywords
- Cell cycle
- Signal
- Smad
- TGF-β
- Tumor suppressor
- Wound healing