Abstract
The Systolic Hypertension in the Elderly Program (SHEP) was a multicenter random-assignment double-blind placebo-controlled clinical trial in persons aged 60 years and older with isolated systolic hypertension (ISH). The results of this study demonstrated that antihypertensive stepped-care drug treatment with low-dose chlorthalidone (as the step 1 medication) reduced the incidence of total stroke by 36%, conferring a 5-year absolute benefit of 30 events per 1000 participants. In addition, measured cardiovascular (CV) events were reduced.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 62-63 |
| Number of pages | 2 |
| Journal | Choices in Cardiology |
| Volume | 8 |
| Issue number | 3 |
| State | Published - 1994 |
All Science Journal Classification (ASJC) codes
- Cardiology and Cardiovascular Medicine