Treatment of neuro-ophthalmic sarcoidosis

Research output: Contribution to journalReview articlepeer-review

7 Scopus citations

Abstract

Background: Because of the rarity of neuro-ophthalmic sarcoidosis, there are no therapeutic guidelines based on evidence-based medicine for this disorder. Evidence Acquisition: Review of literature combined with personal experience. Results: Corticosteroids are the preferred initial therapy for neuro-ophthalmic sarcoidosis. If patients cannot tolerate the requisite dose of corticosteroid needed to control their disease, or if corticosteroids fail to adequately control the disease process, the choices of a second agent are based on the consideration of rapidity of clinical response and the safety profile. Conclusions: Although methotrexate and mycophenolate mofetil are the medications that are often selected after corticosteroid failure, more rapidly acting agents that have been used are infliximab and intravenous cyclophosphamide.

Original languageEnglish (US)
Pages (from-to)65-72
Number of pages8
JournalJournal of Neuro-Ophthalmology
Volume35
Issue number1
DOIs
StatePublished - Mar 28 2015

All Science Journal Classification (ASJC) codes

  • Ophthalmology
  • Clinical Neurology

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