Treatment of phobic neurosis with clomipramine: a controlled clinical trial

J. I. Escobar, R. P. Landbloom

Research output: Contribution to journalArticlepeer-review

29 Scopus citations


A double blind trial compared clomipramine to placebo in the treatment of nine phobic patients for a period of six weeks. Overall, patients on clomipramine showed a larger decrease in phobic symptoms than did patients on placebo. Differences in improvement reached statistical significance only at Day 14 and favored clomipramine over placebo. It was the clinical impression that clomipramine has a positive therapeutic effect on patients with phobic neurosis. However, because of the small sample size, further controlled studies are needed to obtain decisive conclusions.

Original languageEnglish (US)
Pages (from-to)680-685
Number of pages6
JournalCurrent Therapeutic Research - Clinical and Experimental
Issue number5
StatePublished - Dec 1 1976
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Pharmacology
  • Pharmacology (medical)

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