Abstract
Harms of opioid analgesics, especially high-dose therapy among individuals with comorbidities and older age, are increasingly recognized. However, trends in opioid receipt among HIV-infected patients are not well characterized. We examined trends, from 1999 to 2010, in any and high-dose (≥120 mg/day) opioid receipt among patients with and without HIV, by age strata, controlling for demographic and clinical correlates. Of 127,216 patients, 64 % received at least one opioid prescription. Opioid receipt increased substantially among HIV-infected and uninfected patients over the study; high-dose therapy was more prevalent among HIV-infected patients. Trends in high-dose receipt stratified by three age groups revealed an increasing trend in each age strata, higher among HIV-infected patients. Correlates of any opioid receipt included HIV, PTSD and major depression. Correlates of high-dose receipt included HIV, PTSD, major depression and drug use disorders. These findings suggest a need for appropriate balance of risks and benefits, especially as these populations age.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 679-686 |
| Number of pages | 8 |
| Journal | AIDS and behavior |
| Volume | 20 |
| Issue number | 3 |
| DOIs | |
| State | Published - Mar 1 2016 |
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All Science Journal Classification (ASJC) codes
- Social Psychology
- Public Health, Environmental and Occupational Health
- Infectious Diseases
Keywords
- Aging
- Analgesics
- Chronic
- Human immunodeficiency virus
- Opioids
- Pain
Cite this
}
Trends in Any and High-Dose Opioid Analgesic Receipt Among Aging Patients With and Without HIV. / Becker, William C.; Gordon, Kirsha; Jennifer Edelman, E.; Kerns, Robert D.; Crystal, Stephen; Dziura, James D.; Fiellin, Lynn E.; Gordon, Adam J.; Goulet, Joseph L.; Justice, Amy C.; Fiellin, David A.
In: AIDS and behavior, Vol. 20, No. 3, 01.03.2016, p. 679-686.Research output: Contribution to journal › Article
TY - JOUR
T1 - Trends in Any and High-Dose Opioid Analgesic Receipt Among Aging Patients With and Without HIV
AU - Becker, William C.
AU - Gordon, Kirsha
AU - Jennifer Edelman, E.
AU - Kerns, Robert D.
AU - Crystal, Stephen
AU - Dziura, James D.
AU - Fiellin, Lynn E.
AU - Gordon, Adam J.
AU - Goulet, Joseph L.
AU - Justice, Amy C.
AU - Fiellin, David A.
PY - 2016/3/1
Y1 - 2016/3/1
N2 - Harms of opioid analgesics, especially high-dose therapy among individuals with comorbidities and older age, are increasingly recognized. However, trends in opioid receipt among HIV-infected patients are not well characterized. We examined trends, from 1999 to 2010, in any and high-dose (≥120 mg/day) opioid receipt among patients with and without HIV, by age strata, controlling for demographic and clinical correlates. Of 127,216 patients, 64 % received at least one opioid prescription. Opioid receipt increased substantially among HIV-infected and uninfected patients over the study; high-dose therapy was more prevalent among HIV-infected patients. Trends in high-dose receipt stratified by three age groups revealed an increasing trend in each age strata, higher among HIV-infected patients. Correlates of any opioid receipt included HIV, PTSD and major depression. Correlates of high-dose receipt included HIV, PTSD, major depression and drug use disorders. These findings suggest a need for appropriate balance of risks and benefits, especially as these populations age.
AB - Harms of opioid analgesics, especially high-dose therapy among individuals with comorbidities and older age, are increasingly recognized. However, trends in opioid receipt among HIV-infected patients are not well characterized. We examined trends, from 1999 to 2010, in any and high-dose (≥120 mg/day) opioid receipt among patients with and without HIV, by age strata, controlling for demographic and clinical correlates. Of 127,216 patients, 64 % received at least one opioid prescription. Opioid receipt increased substantially among HIV-infected and uninfected patients over the study; high-dose therapy was more prevalent among HIV-infected patients. Trends in high-dose receipt stratified by three age groups revealed an increasing trend in each age strata, higher among HIV-infected patients. Correlates of any opioid receipt included HIV, PTSD and major depression. Correlates of high-dose receipt included HIV, PTSD, major depression and drug use disorders. These findings suggest a need for appropriate balance of risks and benefits, especially as these populations age.
KW - Aging
KW - Analgesics
KW - Chronic
KW - Human immunodeficiency virus
KW - Opioids
KW - Pain
UR - http://www.scopus.com/inward/record.url?scp=84959502802&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84959502802&partnerID=8YFLogxK
U2 - 10.1007/s10461-015-1197-5
DO - 10.1007/s10461-015-1197-5
M3 - Article
C2 - 26384973
AN - SCOPUS:84959502802
VL - 20
SP - 679
EP - 686
JO - AIDS and Behavior
JF - AIDS and Behavior
SN - 1090-7165
IS - 3
ER -