Trends in outcome and hospitalization charges of adult patients admitted with botulism in the United States

Nizar Souayah, Lubna Shafiq Mehyar, Hafiz M.R. Khan, Hussam A. Yacoub, Zaid Abed Al-Kariem A Al-Qudah, Abu Nasar, Zubeda Begum Sheikh, Leila Maybodi, Adnan I. Qureshi

Research output: Contribution to journalArticlepeer-review

9 Scopus citations


Background: To assess the impact of new therapeutic strategies on outcomes and hospitalization charges among adult patients with botulism in the United States. Methods: We determined in-hospital outcomes and charges for patients with botulism hospitalized in 1993-1994 and compared them with those observed among patients hospitalized in 2006-2007. Mortality, length of stay, and hospitalization charges were calculated. Age, sex, race, ethnicity, and discharge status were also reported. Results: There were 66 and 132 admissions of adult patients with botulism in 1993-1994 and 2006-2007, respectively. Men predominance was observed in 2006-2007 compared to women predominance during the 1993-1994 time period. There was no significant difference in the average length of stay and in-hospital mortality rate between the two groups studied. However, in the 2006-2007 group, there was a significant increase in the mean hospitalization charges (USD 126,092 ± 120,535 vs. USD 83,623 ± 82,084; p = 0.0107) and in the proportion of patients requiring mechanical ventilation when compared to 1993-1994 (34 vs. 13.6%; p < 0.0001). Conclusion: Botulism continues to be an infrequent cause of hospitalization, with a significant increase in the average hospitalization charges in 2006-2007 when compared to 1993-1994, despite a nonsignificant change in the mortality rate and average length of hospitalization.

Original languageEnglish (US)
Pages (from-to)233-236
Number of pages4
Issue number4
StatePublished - Jun 2012

All Science Journal Classification (ASJC) codes

  • Epidemiology
  • Clinical Neurology


  • Botulism
  • Hospitalization charges
  • Length of hospitalization
  • Mechanical ventilation
  • Mortality


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