TY - JOUR
T1 - Tuberculosis as a Manifestation of the Acquired Immunodeficiency Syndrome (AIDS)
AU - Sunderam, Gnana
AU - McDonald, Reynard J.
AU - Maniatis, Theodore
AU - Oleske, James
AU - Kapila, Rajendra
AU - Reichman, Lee B.
PY - 1986/7/18
Y1 - 1986/7/18
N2 - Tuberculosis has not been well documented as a complication of the acquired immunodeficiency syndrome (AIDS). We studied 48 cases of mycobacterial diseases among a group of 136 adult patients with AIDS over a 43-month period. Twenty-nine of them had severe and unusual manifestations of disease due to Mycobacterium tuberculosis, predominantly extrapulmonary and disseminated. Tuberculosis was more common among Haitians (4/8) and intravenous drug abusers (24/102) than among homosexuals who did not abuse drugs (0/22). Twelve of 21 patients with tuberculosis who were treated responded well, whereas three developed progressive disease indicative of treatment failure. Severe and unusual presentation of overwhelming tuberculosis in appropriate clinical circumstances may be considered an infection predictive of the presence of AIDS.
AB - Tuberculosis has not been well documented as a complication of the acquired immunodeficiency syndrome (AIDS). We studied 48 cases of mycobacterial diseases among a group of 136 adult patients with AIDS over a 43-month period. Twenty-nine of them had severe and unusual manifestations of disease due to Mycobacterium tuberculosis, predominantly extrapulmonary and disseminated. Tuberculosis was more common among Haitians (4/8) and intravenous drug abusers (24/102) than among homosexuals who did not abuse drugs (0/22). Twelve of 21 patients with tuberculosis who were treated responded well, whereas three developed progressive disease indicative of treatment failure. Severe and unusual presentation of overwhelming tuberculosis in appropriate clinical circumstances may be considered an infection predictive of the presence of AIDS.
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U2 - 10.1001/jama.1986.03380030064029
DO - 10.1001/jama.1986.03380030064029
M3 - Article
C2 - 3723722
AN - SCOPUS:84944285035
SN - 0098-7484
VL - 256
SP - 362
EP - 366
JO - JAMA: The Journal of the American Medical Association
JF - JAMA: The Journal of the American Medical Association
IS - 3
ER -