Tumorigenic activity of cloned polyoma virus DNA in newborn rats

C. Gélinas, L. Bouchard, M. Bastin

Research output: Contribution to journalArticle

6 Scopus citations


The proximal portion of the polyoma virus early region as well as the complete viral genome were cloned in pBR322. Recombinant plasmids induced tumors in newborn rats but only after linearization of the DNA by various restriction endonucleases.

Original languageEnglish (US)
Pages (from-to)1074-1075
Number of pages2
Issue number10
StatePublished - Oct 1 1981
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Biochemistry, Genetics and Molecular Biology(all)

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