Two volatile-phase alcohols inhibit growth of Pseudogymnoascus destructans, causative agent of white-nose syndrome in bats

Sally Padhi, Itamar Dias, Joan W. Bennett

Research output: Contribution to journalArticlepeer-review

6 Scopus citations

Abstract

In North America, Pseudogymnoascus destructans infects hibernating bats within caves and other hibernacula causing high mortalities. We have sought a potential fumigation strategy that can be deployed within a contained area, using an agent that already has been determined to be safe for environmental application. We here report the efficacy of 1-octen-3-ol (“mushroom alcohol”) and 1-hexanol against P. destructans. At 50 ppm and 100 ppm, vapours of racemic 1-octen-3-ol are fungicidal to P. destructans at 15ºC after 21 days incubation, while exposure to 5 and 10 ppm is fungistatic. The six-carbon alcohol 1-hexanol is not as effective, although at 50 and 100 ppm, vapours of this compound inhibited growth of the fungus.

Original languageEnglish (US)
Pages (from-to)11-16
Number of pages6
JournalMycology
Volume8
Issue number1
DOIs
StatePublished - Jan 2 2017

All Science Journal Classification (ASJC) codes

  • Microbiology
  • Infectious Diseases

Keywords

  • 1-hexanol
  • 1-octen-3-ol
  • Pseudogymnoascus destructans
  • bats
  • mushroom alcohol
  • white-nose syndrome

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