Ultra-high speed and ultra-high resolution spectral-domain optical coherence tomography and optical Doppler tomography in ophthalmology.

B. Cense, T. C. Chen, N. Nassif, M. C. Pierce, S. H. Yun, B. H. Park, B. E. Bouma, G. J. Tearney, J. F. de Boer

Research output: Contribution to journalArticlepeer-review

27 Scopus citations

Abstract

We present ultra-high resolution optical coherence tomography (OCT) structural intensity and optical Doppler tomography (ODT) flow velocity images of the human retina in vivo. The ultra-high speed OCT system is based on Spectral Domain or Fourier Domain technology, which provides a sensitivity advantage over conventional OCT of more than 2 orders of magnitude. This sensitivity improvement allows video rate OCT and ODT cross sectional imaging of retinal structures. Images will be presented with axial resolutions of 6 and 3.5 microns. We observed small features in the inner and outer plexiform layers, which are believed to be small blood vessels. Flow velocity images will be presented showing pulsatile flow in retinal arteries and veins.

Original languageEnglish (US)
Pages (from-to)123-132
Number of pages10
JournalBulletin de la Société belge d'ophtalmologie
Issue number302
StatePublished - 2006
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Ophthalmology
  • Sensory Systems

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