Unexpected functional consequences of the loss of the autophagy-related conjugation system

Toshiro Saito; Junichi Sadoshima

doi:10.1161/CIRCRESAHA.117.310450

Unexpected functional consequences of the loss of the autophagy-related conjugation system

Toshiro Saito, Junichi Sadoshima

Research output: Contribution to journal › Review article › peer-review

2 Scopus citations

Abstract

We discuss the recent finding by Mizishima's group regarding the role of the autophagy-related conjugation system in mediating the closure of autophagosomes and its implication in the study of autophagy in mammalian cells. The study not only shows a novel function of the autophagy-related conjugation system but also indicates that mammalian cells are capable of generating autophagosomes even without it.

Original language	English (US)
Pages (from-to)	610-612
Number of pages	3
Journal	Circulation research
Volume	120
Issue number	4
DOIs	https://doi.org/10.1161/CIRCRESAHA.117.310450
State	Published - Feb 17 2017

All Science Journal Classification (ASJC) codes

Physiology
Cardiology and Cardiovascular Medicine

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10.1161/CIRCRESAHA.117.310450

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title = "Unexpected functional consequences of the loss of the autophagy-related conjugation system",

abstract = "We discuss the recent finding by Mizishima's group regarding the role of the autophagy-related conjugation system in mediating the closure of autophagosomes and its implication in the study of autophagy in mammalian cells. The study not only shows a novel function of the autophagy-related conjugation system but also indicates that mammalian cells are capable of generating autophagosomes even without it.",

author = "Toshiro Saito and Junichi Sadoshima",

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AB - We discuss the recent finding by Mizishima's group regarding the role of the autophagy-related conjugation system in mediating the closure of autophagosomes and its implication in the study of autophagy in mammalian cells. The study not only shows a novel function of the autophagy-related conjugation system but also indicates that mammalian cells are capable of generating autophagosomes even without it.

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Unexpected functional consequences of the loss of the autophagy-related conjugation system

Abstract

All Science Journal Classification (ASJC) codes

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