Unexpected functional consequences of the loss of the autophagy-related conjugation system

Toshiro Saito, Junichi Sadoshima

Research output: Contribution to journalReview article

1 Scopus citations

Abstract

We discuss the recent finding by Mizishima's group regarding the role of the autophagy-related conjugation system in mediating the closure of autophagosomes and its implication in the study of autophagy in mammalian cells. The study not only shows a novel function of the autophagy-related conjugation system but also indicates that mammalian cells are capable of generating autophagosomes even without it.

Original languageEnglish (US)
Pages (from-to)610-612
Number of pages3
JournalCirculation research
Volume120
Issue number4
DOIs
StatePublished - Feb 17 2017

All Science Journal Classification (ASJC) codes

  • Physiology
  • Cardiology and Cardiovascular Medicine

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