Unexpected functional consequences of the loss of the autophagy-related conjugation system

Toshiro Saito, Junichi Sadoshima

Research output: Contribution to journalReview article

Abstract

We discuss the recent finding by Mizishima's group regarding the role of the autophagy-related conjugation system in mediating the closure of autophagosomes and its implication in the study of autophagy in mammalian cells. The study not only shows a novel function of the autophagy-related conjugation system but also indicates that mammalian cells are capable of generating autophagosomes even without it.

Original languageEnglish (US)
Pages (from-to)610-612
Number of pages3
JournalCirculation research
Volume120
Issue number4
DOIs
StatePublished - Feb 17 2017

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Autophagy
Autophagosomes

All Science Journal Classification (ASJC) codes

  • Physiology
  • Cardiology and Cardiovascular Medicine

Cite this

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abstract = "We discuss the recent finding by Mizishima's group regarding the role of the autophagy-related conjugation system in mediating the closure of autophagosomes and its implication in the study of autophagy in mammalian cells. The study not only shows a novel function of the autophagy-related conjugation system but also indicates that mammalian cells are capable of generating autophagosomes even without it.",
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Unexpected functional consequences of the loss of the autophagy-related conjugation system. / Saito, Toshiro; Sadoshima, Junichi.

In: Circulation research, Vol. 120, No. 4, 17.02.2017, p. 610-612.

Research output: Contribution to journalReview article

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