Use of an open-reading frame-specific Campylobacter jejuni DNA microarray as a new genotyping tool for studying epidemiologically related isolates

Edward E. Leonard; Tohru Takata; Martin J. Blaser; Stanley Falkow; Lucy S. Tompkins; Erin C. Gaynor

doi:10.1086/368268

Use of an open-reading frame-specific Campylobacter jejuni DNA microarray as a new genotyping tool for studying epidemiologically related isolates

Edward E. Leonard, Tohru Takata, Martin J. Blaser, Stanley Falkow, Lucy S. Tompkins, Erin C. Gaynor

Research output: Contribution to journal › Article › peer-review

72 Scopus citations

Abstract

Findings from use of an open-reading frame-specific Campylobacter jejuni DNA microarray to investigate genetic diversity among clinical isolates associated with 5 independent clusters of infection were compared with data from random amplified polymeric DNA (RAPD) and Penner serotyping analyses. The DNA microarray provides a highly specific epidemiological typing tool for analysis of C. jejuni isolates and reveals both divergent and highly conserved gene classes among isolates.

Original language	English (US)
Pages (from-to)	691-694
Number of pages	4
Journal	Journal of Infectious Diseases
Volume	187
Issue number	4
DOIs	https://doi.org/10.1086/368268
State	Published - Feb 15 2003
Externally published	Yes

All Science Journal Classification (ASJC) codes

Immunology and Allergy
Infectious Diseases

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10.1086/368268

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title = "Use of an open-reading frame-specific Campylobacter jejuni DNA microarray as a new genotyping tool for studying epidemiologically related isolates",

abstract = "Findings from use of an open-reading frame-specific Campylobacter jejuni DNA microarray to investigate genetic diversity among clinical isolates associated with 5 independent clusters of infection were compared with data from random amplified polymeric DNA (RAPD) and Penner serotyping analyses. The DNA microarray provides a highly specific epidemiological typing tool for analysis of C. jejuni isolates and reveals both divergent and highly conserved gene classes among isolates.",

author = "Leonard, {Edward E.} and Tohru Takata and Blaser, {Martin J.} and Stanley Falkow and Tompkins, {Lucy S.} and Gaynor, {Erin C.}",

note = "Funding Information: Financial support: Howard Hughes Postdoctoral Research Fellowship for Physicians and Minority Medical Faculty Development Award, Robert Wood Johnson Foundation (to E.E.L.); Schering-Plough Research Institute Fellow of the Life Sciences Research Foundation (to E.C.G.); National Institutes of Health (RO1 AI24145 to M.J.B. and RO1 AI38459 to L.S.T.); Medical Research Service of the Department of Veterans Affairs (to M.J.B.).",

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doi = "10.1086/368268",

language = "English (US)",

volume = "187",

pages = "691--694",

journal = "Journal of Infectious Diseases",

issn = "0022-1899",

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Use of an open-reading frame-specific Campylobacter jejuni DNA microarray as a new genotyping tool for studying epidemiologically related isolates. / Leonard, Edward E.; Takata, Tohru; Blaser, Martin J.; Falkow, Stanley; Tompkins, Lucy S.; Gaynor, Erin C.

In: Journal of Infectious Diseases, Vol. 187, No. 4, 15.02.2003, p. 691-694.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Use of an open-reading frame-specific Campylobacter jejuni DNA microarray as a new genotyping tool for studying epidemiologically related isolates

AU - Leonard, Edward E.

AU - Takata, Tohru

AU - Blaser, Martin J.

AU - Falkow, Stanley

AU - Tompkins, Lucy S.

AU - Gaynor, Erin C.

N1 - Funding Information: Financial support: Howard Hughes Postdoctoral Research Fellowship for Physicians and Minority Medical Faculty Development Award, Robert Wood Johnson Foundation (to E.E.L.); Schering-Plough Research Institute Fellow of the Life Sciences Research Foundation (to E.C.G.); National Institutes of Health (RO1 AI24145 to M.J.B. and RO1 AI38459 to L.S.T.); Medical Research Service of the Department of Veterans Affairs (to M.J.B.).

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Use of an open-reading frame-specific Campylobacter jejuni DNA microarray as a new genotyping tool for studying epidemiologically related isolates

Abstract

All Science Journal Classification (ASJC) codes

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