Use of an open-reading frame-specific Campylobacter jejuni DNA microarray as a new genotyping tool for studying epidemiologically related isolates

Edward E. Leonard; Tohru Takata; Martin J. Blaser; Stanley Falkow; Lucy S. Tompkins; Erin C. Gaynor

doi:10.1086/368268

Use of an open-reading frame-specific Campylobacter jejuni DNA microarray as a new genotyping tool for studying epidemiologically related isolates

Edward E. Leonard, Tohru Takata, Martin J. Blaser, Stanley Falkow, Lucy S. Tompkins, Erin C. Gaynor

Research output: Contribution to journal › Article › peer-review

72 Scopus citations

Abstract

Findings from use of an open-reading frame-specific Campylobacter jejuni DNA microarray to investigate genetic diversity among clinical isolates associated with 5 independent clusters of infection were compared with data from random amplified polymeric DNA (RAPD) and Penner serotyping analyses. The DNA microarray provides a highly specific epidemiological typing tool for analysis of C. jejuni isolates and reveals both divergent and highly conserved gene classes among isolates.

Original language	English (US)
Pages (from-to)	691-694
Number of pages	4
Journal	Journal of Infectious Diseases
Volume	187
Issue number	4
DOIs	https://doi.org/10.1086/368268
State	Published - Feb 15 2003
Externally published	Yes

All Science Journal Classification (ASJC) codes

Immunology and Allergy
Infectious Diseases

Access to Document

10.1086/368268

Cite this

@article{8522eff851924680a2ba7bdc6f7576fa,

title = "Use of an open-reading frame-specific Campylobacter jejuni DNA microarray as a new genotyping tool for studying epidemiologically related isolates",

abstract = "Findings from use of an open-reading frame-specific Campylobacter jejuni DNA microarray to investigate genetic diversity among clinical isolates associated with 5 independent clusters of infection were compared with data from random amplified polymeric DNA (RAPD) and Penner serotyping analyses. The DNA microarray provides a highly specific epidemiological typing tool for analysis of C. jejuni isolates and reveals both divergent and highly conserved gene classes among isolates.",

author = "Leonard, {Edward E.} and Tohru Takata and Blaser, {Martin J.} and Stanley Falkow and Tompkins, {Lucy S.} and Gaynor, {Erin C.}",

note = "Funding Information: Financial support: Howard Hughes Postdoctoral Research Fellowship for Physicians and Minority Medical Faculty Development Award, Robert Wood Johnson Foundation (to E.E.L.); Schering-Plough Research Institute Fellow of the Life Sciences Research Foundation (to E.C.G.); National Institutes of Health (RO1 AI24145 to M.J.B. and RO1 AI38459 to L.S.T.); Medical Research Service of the Department of Veterans Affairs (to M.J.B.).",

year = "2003",

month = feb,

day = "15",

doi = "10.1086/368268",

language = "English (US)",

volume = "187",

pages = "691--694",

journal = "Journal of Infectious Diseases",

issn = "0022-1899",

publisher = "Oxford University Press",

number = "4",

}

TY - JOUR

T1 - Use of an open-reading frame-specific Campylobacter jejuni DNA microarray as a new genotyping tool for studying epidemiologically related isolates

AU - Leonard, Edward E.

AU - Takata, Tohru

AU - Blaser, Martin J.

AU - Falkow, Stanley

AU - Tompkins, Lucy S.

AU - Gaynor, Erin C.

N1 - Funding Information: Financial support: Howard Hughes Postdoctoral Research Fellowship for Physicians and Minority Medical Faculty Development Award, Robert Wood Johnson Foundation (to E.E.L.); Schering-Plough Research Institute Fellow of the Life Sciences Research Foundation (to E.C.G.); National Institutes of Health (RO1 AI24145 to M.J.B. and RO1 AI38459 to L.S.T.); Medical Research Service of the Department of Veterans Affairs (to M.J.B.).

PY - 2003/2/15

Y1 - 2003/2/15

N2 - Findings from use of an open-reading frame-specific Campylobacter jejuni DNA microarray to investigate genetic diversity among clinical isolates associated with 5 independent clusters of infection were compared with data from random amplified polymeric DNA (RAPD) and Penner serotyping analyses. The DNA microarray provides a highly specific epidemiological typing tool for analysis of C. jejuni isolates and reveals both divergent and highly conserved gene classes among isolates.

AB - Findings from use of an open-reading frame-specific Campylobacter jejuni DNA microarray to investigate genetic diversity among clinical isolates associated with 5 independent clusters of infection were compared with data from random amplified polymeric DNA (RAPD) and Penner serotyping analyses. The DNA microarray provides a highly specific epidemiological typing tool for analysis of C. jejuni isolates and reveals both divergent and highly conserved gene classes among isolates.

UR - http://www.scopus.com/inward/record.url?scp=0037443063&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0037443063&partnerID=8YFLogxK

U2 - 10.1086/368268

DO - 10.1086/368268

M3 - Article

C2 - 12599089

AN - SCOPUS:0037443063

VL - 187

SP - 691

EP - 694

JO - Journal of Infectious Diseases

JF - Journal of Infectious Diseases

SN - 0022-1899

IS - 4

ER -

Use of an open-reading frame-specific Campylobacter jejuni DNA microarray as a new genotyping tool for studying epidemiologically related isolates

Abstract

All Science Journal Classification (ASJC) codes

Access to Document

Other files and links

Fingerprint

Cite this