Use of an open-reading frame-specific Campylobacter jejuni DNA microarray as a new genotyping tool for studying epidemiologically related isolates

Edward E. Leonard, Tohru Takata, Martin J. Blaser, Stanley Falkow, Lucy S. Tompkins, Erin C. Gaynor

Research output: Contribution to journalArticlepeer-review

72 Scopus citations

Abstract

Findings from use of an open-reading frame-specific Campylobacter jejuni DNA microarray to investigate genetic diversity among clinical isolates associated with 5 independent clusters of infection were compared with data from random amplified polymeric DNA (RAPD) and Penner serotyping analyses. The DNA microarray provides a highly specific epidemiological typing tool for analysis of C. jejuni isolates and reveals both divergent and highly conserved gene classes among isolates.

Original languageEnglish (US)
Pages (from-to)691-694
Number of pages4
JournalJournal of Infectious Diseases
Volume187
Issue number4
DOIs
StatePublished - Feb 15 2003
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Immunology and Allergy
  • Infectious Diseases

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