Use of Dihydroergotamine in Patients with Postconcussion Syndrome

Juanita G. McBeath, Anil Nanda

Research output: Contribution to journalArticle

37 Scopus citations

Abstract

SYNOPSIS The experience with 34 patients who came to the Shreveport Headache Clinic for treatment of postconcussion headache is reviewed. All had been suffering from postconcussion (posttraumatic) syndrome for periods ranging from one day to more than three years, and all displayed, in addition to headache, at least three other symptoms characteristic of the syndrome, eg, memory problems, impaired concentration, sleep problems, dizziness, and anxiety. After initial evaluation at the clinic, the patients were admitted to Willis Knighton Medical Center and treated with repetitive administration of intravenous dihydroergotamine (DHE) and metoclopramide. A good to excellent overall response to DHE therapy was achieved by 88% (29) of the patients. The percentages and numbers of patients obtaining good to excellent relief of selected key symptoms were: 85% (28) ‐ headache, 91% (30) ‐ memory problems, 94% (31) ‐ sleep problems, and 88% (29) ‐ dizziness. DHE was well‐tolerated, and no serious or unexpected adverse reactions were reported. The most frequently reported adverse reactions were mild nausea and brief worsening of headache.

Original languageEnglish (US)
Pages (from-to)148-151
Number of pages4
JournalHeadache: The Journal of Head and Face Pain
Volume34
Issue number3
DOIs
StatePublished - Jan 1 1994
Externally publishedYes

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All Science Journal Classification (ASJC) codes

  • Neurology
  • Clinical Neurology

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