Use of Dihydroergotamine in Patients with Postconcussion Syndrome

Juanita G. McBeath, Anil Nanda

Research output: Contribution to journalArticle

37 Citations (Scopus)

Abstract

SYNOPSIS The experience with 34 patients who came to the Shreveport Headache Clinic for treatment of postconcussion headache is reviewed. All had been suffering from postconcussion (posttraumatic) syndrome for periods ranging from one day to more than three years, and all displayed, in addition to headache, at least three other symptoms characteristic of the syndrome, eg, memory problems, impaired concentration, sleep problems, dizziness, and anxiety. After initial evaluation at the clinic, the patients were admitted to Willis Knighton Medical Center and treated with repetitive administration of intravenous dihydroergotamine (DHE) and metoclopramide. A good to excellent overall response to DHE therapy was achieved by 88% (29) of the patients. The percentages and numbers of patients obtaining good to excellent relief of selected key symptoms were: 85% (28) ‐ headache, 91% (30) ‐ memory problems, 94% (31) ‐ sleep problems, and 88% (29) ‐ dizziness. DHE was well‐tolerated, and no serious or unexpected adverse reactions were reported. The most frequently reported adverse reactions were mild nausea and brief worsening of headache.

Original languageEnglish (US)
Pages (from-to)148-151
Number of pages4
JournalHeadache: The Journal of Head and Face Pain
Volume34
Issue number3
DOIs
StatePublished - Jan 1 1994
Externally publishedYes

Fingerprint

Dihydroergotamine
Headache
Dizziness
Sleep
Metoclopramide
Intravenous Administration
Nausea
Anxiety
Therapeutics

All Science Journal Classification (ASJC) codes

  • Neurology
  • Clinical Neurology

Cite this

@article{55e66c1063124b73a6ba41a0d2bcc390,
title = "Use of Dihydroergotamine in Patients with Postconcussion Syndrome",
abstract = "SYNOPSIS The experience with 34 patients who came to the Shreveport Headache Clinic for treatment of postconcussion headache is reviewed. All had been suffering from postconcussion (posttraumatic) syndrome for periods ranging from one day to more than three years, and all displayed, in addition to headache, at least three other symptoms characteristic of the syndrome, eg, memory problems, impaired concentration, sleep problems, dizziness, and anxiety. After initial evaluation at the clinic, the patients were admitted to Willis Knighton Medical Center and treated with repetitive administration of intravenous dihydroergotamine (DHE) and metoclopramide. A good to excellent overall response to DHE therapy was achieved by 88{\%} (29) of the patients. The percentages and numbers of patients obtaining good to excellent relief of selected key symptoms were: 85{\%} (28) ‐ headache, 91{\%} (30) ‐ memory problems, 94{\%} (31) ‐ sleep problems, and 88{\%} (29) ‐ dizziness. DHE was well‐tolerated, and no serious or unexpected adverse reactions were reported. The most frequently reported adverse reactions were mild nausea and brief worsening of headache.",
author = "McBeath, {Juanita G.} and Anil Nanda",
year = "1994",
month = "1",
day = "1",
doi = "10.1111/j.1526-4610.1994.hed3403148.x",
language = "English (US)",
volume = "34",
pages = "148--151",
journal = "Headache",
issn = "0017-8748",
publisher = "Wiley-Blackwell",
number = "3",

}

Use of Dihydroergotamine in Patients with Postconcussion Syndrome. / McBeath, Juanita G.; Nanda, Anil.

In: Headache: The Journal of Head and Face Pain, Vol. 34, No. 3, 01.01.1994, p. 148-151.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Use of Dihydroergotamine in Patients with Postconcussion Syndrome

AU - McBeath, Juanita G.

AU - Nanda, Anil

PY - 1994/1/1

Y1 - 1994/1/1

N2 - SYNOPSIS The experience with 34 patients who came to the Shreveport Headache Clinic for treatment of postconcussion headache is reviewed. All had been suffering from postconcussion (posttraumatic) syndrome for periods ranging from one day to more than three years, and all displayed, in addition to headache, at least three other symptoms characteristic of the syndrome, eg, memory problems, impaired concentration, sleep problems, dizziness, and anxiety. After initial evaluation at the clinic, the patients were admitted to Willis Knighton Medical Center and treated with repetitive administration of intravenous dihydroergotamine (DHE) and metoclopramide. A good to excellent overall response to DHE therapy was achieved by 88% (29) of the patients. The percentages and numbers of patients obtaining good to excellent relief of selected key symptoms were: 85% (28) ‐ headache, 91% (30) ‐ memory problems, 94% (31) ‐ sleep problems, and 88% (29) ‐ dizziness. DHE was well‐tolerated, and no serious or unexpected adverse reactions were reported. The most frequently reported adverse reactions were mild nausea and brief worsening of headache.

AB - SYNOPSIS The experience with 34 patients who came to the Shreveport Headache Clinic for treatment of postconcussion headache is reviewed. All had been suffering from postconcussion (posttraumatic) syndrome for periods ranging from one day to more than three years, and all displayed, in addition to headache, at least three other symptoms characteristic of the syndrome, eg, memory problems, impaired concentration, sleep problems, dizziness, and anxiety. After initial evaluation at the clinic, the patients were admitted to Willis Knighton Medical Center and treated with repetitive administration of intravenous dihydroergotamine (DHE) and metoclopramide. A good to excellent overall response to DHE therapy was achieved by 88% (29) of the patients. The percentages and numbers of patients obtaining good to excellent relief of selected key symptoms were: 85% (28) ‐ headache, 91% (30) ‐ memory problems, 94% (31) ‐ sleep problems, and 88% (29) ‐ dizziness. DHE was well‐tolerated, and no serious or unexpected adverse reactions were reported. The most frequently reported adverse reactions were mild nausea and brief worsening of headache.

UR - http://www.scopus.com/inward/record.url?scp=0028260152&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0028260152&partnerID=8YFLogxK

U2 - 10.1111/j.1526-4610.1994.hed3403148.x

DO - 10.1111/j.1526-4610.1994.hed3403148.x

M3 - Article

C2 - 8200788

AN - SCOPUS:0028260152

VL - 34

SP - 148

EP - 151

JO - Headache

JF - Headache

SN - 0017-8748

IS - 3

ER -