Abstract
The use of isotopic carbon dioxide lasers for determination of carbon (and oxygen) isotope ratios was first demonstrated in 1994. Since then a commercial device called LARA™, has been manufactured and used for Helicobacter pylori breath tests using 13C-labelled urea. The major advantages of the optogalvanic effect compared with other infrared absorption isotope ratio measurement techniques are its lack of optical background and its high sensitivity resulting from a signal gain proportional to laser power. Continuous normalisation using two cells, a standard and sample, lead to high accuracy as well as precision. Recent advances in continuous flow measurement of 13C/12C ratios of CO2 in air and extensions of the technique to 14C, which can be analysed as a stable isotope, are described.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 363-371 |
| Number of pages | 9 |
| Journal | Isotopes in Environmental and Health Studies |
| Volume | 41 |
| Issue number | 4 |
| DOIs | |
| State | Published - Dec 1 2005 |
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All Science Journal Classification (ASJC) codes
- Environmental Chemistry
- Environmental Science(all)
- Inorganic Chemistry
Keywords
- Carbon dioxide
- Carbon-13
- Carbon-14
- IR spectrometry
- Isotope analysis
- Isotopic carbon dioxide lasers
- Optogalvanic detection
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Use of the optogalvanic effect (OGE) for isotope ratio spectrometry of 13CO2 and 14CO2. / Murnick, Daniel E.; Okil, Joseph O.
In: Isotopes in Environmental and Health Studies, Vol. 41, No. 4, 01.12.2005, p. 363-371.Research output: Contribution to journal › Article
TY - JOUR
T1 - Use of the optogalvanic effect (OGE) for isotope ratio spectrometry of 13CO2 and 14CO2
AU - Murnick, Daniel E.
AU - Okil, Joseph O.
PY - 2005/12/1
Y1 - 2005/12/1
N2 - The use of isotopic carbon dioxide lasers for determination of carbon (and oxygen) isotope ratios was first demonstrated in 1994. Since then a commercial device called LARA™, has been manufactured and used for Helicobacter pylori breath tests using 13C-labelled urea. The major advantages of the optogalvanic effect compared with other infrared absorption isotope ratio measurement techniques are its lack of optical background and its high sensitivity resulting from a signal gain proportional to laser power. Continuous normalisation using two cells, a standard and sample, lead to high accuracy as well as precision. Recent advances in continuous flow measurement of 13C/12C ratios of CO2 in air and extensions of the technique to 14C, which can be analysed as a stable isotope, are described.
AB - The use of isotopic carbon dioxide lasers for determination of carbon (and oxygen) isotope ratios was first demonstrated in 1994. Since then a commercial device called LARA™, has been manufactured and used for Helicobacter pylori breath tests using 13C-labelled urea. The major advantages of the optogalvanic effect compared with other infrared absorption isotope ratio measurement techniques are its lack of optical background and its high sensitivity resulting from a signal gain proportional to laser power. Continuous normalisation using two cells, a standard and sample, lead to high accuracy as well as precision. Recent advances in continuous flow measurement of 13C/12C ratios of CO2 in air and extensions of the technique to 14C, which can be analysed as a stable isotope, are described.
KW - Carbon dioxide
KW - Carbon-13
KW - Carbon-14
KW - IR spectrometry
KW - Isotope analysis
KW - Isotopic carbon dioxide lasers
KW - Optogalvanic detection
UR - http://www.scopus.com/inward/record.url?scp=30644478271&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=30644478271&partnerID=8YFLogxK
U2 - 10.1080/10256010500384440
DO - 10.1080/10256010500384440
M3 - Article
C2 - 16543191
AN - SCOPUS:30644478271
VL - 41
SP - 363
EP - 371
JO - Isotopes in Environmental and Health Studies
JF - Isotopes in Environmental and Health Studies
SN - 1025-6016
IS - 4
ER -