Using consensus OPCRIT diagnoses: An efficient procedure for best- estimate lifetime diagnoses

Maria Helena Azevedo, M. J. Soares, I. Coelho, A. Dourado, J. Valente, A. Macedo, M. Pato, C. Pato

Research output: Contribution to journalArticlepeer-review

58 Scopus citations


Background: The Operational criteria Checklist (OPCRIT) generates diagnoses according to 12 operational diagnostic systems (e.g. DSM-III, DSM- III- R, Research Diagnostic Criteria, ICD- 10). Aims: To examine the agreement between diagnoses generated by the OPCRIT, as completed by the interviewer, with a best-estimate lifetime procedure using the OPCRIT. Method Subjects came from large multi-generational bipolar or schizophrenia pedigrees (n=100), and from a sample of unrelated subjects with schizophrenia (n=40). We analysed the diagnostic agreement between OPCRIT diagnoses generated by the interviewer and our best-estimate OPCRIT diagnoses, according to DSM-III- R and ICD- 10, using Cohen kappa statistics. Results Excellent agreement was found between interviewer OPCRIT diagnoses and OPCRIT diagnoses made by the best-estimate lifetime consensus procedure for DSM- III-R (κ=0.83) and ICD-10 (κ=0.81). Conclusions: Results suggest that this procedure for diagnostic assessment is an efficient alternative to classic best-estimate diagnosis procedures. Declaration of interest: Supported by grants from Junta Nacional de Investigacao Cientifica e Technologia and the US National Institute of Mental Health.

Original languageEnglish (US)
Pages (from-to)154-157
Number of pages4
JournalBritish Journal of Psychiatry
Issue numberAUG.
StatePublished - 1999
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Psychiatry and Mental health


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