Validation of myocardial elastography using MR tagging in normal and abnormal human hearts in vivo

Wei Ning Lee, Zhen Qian, Christina L. Tosti, Srirama V. Swaminathan, Truman R. Brown, Dimitri Metaxas, Elisa E. Konofagou

Research output: Chapter in Book/Report/Conference proceedingConference contribution

3 Scopus citations

Abstract

In this paper, Myocardial Elastography (ME), a radio-frequency (RF) based speckle tracking technique, was employed in order to assess the contractility of a myocardium, and validated against tagged Magnetic Resonance Imaging (tMRI) in vivo in normal as well as abnormal cases. Both RF ultrasound and tMRI frames were acquired in 2D short-axis (SA) views from two healthy subjects and one with a history of infarction. In-plane (lateral and axial) incremental displacements were iteratively estimated using ID cross-correlation and recorrelation techniques in a 2D search with a 1D matching kernel. The incremental displacements from end-diastole (ED) to end-systole (ES) were then accumulated to obtain cumulative systolic displacements. In tMRI, cardiac motion was obtained by a template-matching algorithm on a 2D grid-shaped mesh. The entire displacement distribution within the myocardium was obtained by a cubic B-spline-based method. In both ME and tMRI, 2D Lagrangian finite systolic strains were calculated from cumulative 2D displacements. Radial and circumferential strains were then computed from the 2D finite strains. Both qualitatively and quantitatively, ME is shown capable of measuring myocardial deformation in excellent agreement with tMRI estimates in normal and abnormal subjects.

Original languageEnglish (US)
Title of host publication2007 4th IEEE International Symposium on Biomedical Imaging
Subtitle of host publicationFrom Nano to Macro - Proceedings
Pages384-387
Number of pages4
DOIs
StatePublished - Nov 27 2007
Event2007 4th IEEE International Symposium on Biomedical Imaging: From Nano to Macro; ISBI'07 - Arlington, VA, United States
Duration: Apr 12 2007Apr 15 2007

Publication series

Name2007 4th IEEE International Symposium on Biomedical Imaging: From Nano to Macro - Proceedings

Other

Other2007 4th IEEE International Symposium on Biomedical Imaging: From Nano to Macro; ISBI'07
CountryUnited States
CityArlington, VA
Period4/12/074/15/07

All Science Journal Classification (ASJC) codes

  • Electrical and Electronic Engineering
  • Medicine(all)

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