Vapor deposition of intact polyethylene glycol thin films

D. M. Bubb, B. R. Ringeisen, J. H. Callahan, M. Galicia, A. Vertes, J. S. Horwitz, R. A. McGill, E. J. Houser, P. K. Wu, A. Piqué, D. B. Chrisey

Research output: Contribution to journalArticlepeer-review

53 Scopus citations

Abstract

Thin films of polyethylene glycol (PEG) of average molecular weight, 1400 amu, were deposited by both matrixassisted pulsed laser evaporation (MAPLE) and pulsed laser deposition (PLD). The deposition was carried out in vacuum (∼ 10-6 Torr) with an ArF (λ= 193 nm) laser at a fluence between 150 and 300 mJ/cm2. Films were deposited on NaCl plates, Si(111) wafers, and glass slides. The physiochemical properties of the films are compared via Fourier transform infrared spectroscopy (FTIR), electrospray ionization (ESI) mass spectrometry, and matrix-assisted laser desorption and ionization (MALDI) time-of-flight mass spectrometry. The results show that the MAPLE films nearly identically resemble the starting material, whereas the PLD films do not. These results are discussed within the context of biomedical applications such as drug delivery coatings and in vivo applications where there is a need for transfer of polymeric coatings of PEG without significant chemical modification.

Original languageEnglish (US)
Pages (from-to)121-123
Number of pages3
JournalApplied Physics A: Materials Science and Processing
Volume73
Issue number1
DOIs
StatePublished - 2001

All Science Journal Classification (ASJC) codes

  • Chemistry(all)
  • Materials Science(all)

Fingerprint Dive into the research topics of 'Vapor deposition of intact polyethylene glycol thin films'. Together they form a unique fingerprint.

Cite this