Variation in Emax of the left ventricle among mammals

Gary M. Drzewiecki, Natalia Krawciw, John K.J. Li, Walter Welkowitz

Research output: Contribution to journalConference articlepeer-review


A mechanical relationship is provided that expresses the maximum elastance of the left ventricle in terms of its muscle volume or mass. The relation is derived assuming that the function of the cardiac sarcomere is invariant among different species of mammals. The nonlinear geometric functions are linearized for application to the linear time-varying elastance model of the heart. The results indicate that elastance, Emax, increases with decreasing muscle volume, Vmus, in an approximately logarithmic manner. The computed values of elastance are in good agreement with the data for various mammals. The analysis permits the prediction of Emax across species boundaries and permits its normalization due to variation in heart size, without assuming preload and afterload.

Original languageEnglish (US)
Pages (from-to)110-111
Number of pages2
JournalAnnual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
Volume11 pt 1
StatePublished - Nov 1989
EventImages of the Twenty-First Century - Proceedings of the 11th Annual International Conference of the IEEE Engineering in Medicine and Biology Society. Part 1 - Seattle, WA, USA
Duration: Nov 9 1989Nov 12 1989

All Science Journal Classification (ASJC) codes

  • Signal Processing
  • Biomedical Engineering
  • Computer Vision and Pattern Recognition
  • Health Informatics


Dive into the research topics of 'Variation in E<sub>max</sub> of the left ventricle among mammals'. Together they form a unique fingerprint.

Cite this