Ventilatory responses to carbon dioxide in infants at risk for sudden infant death syndrome

M. A. Graff, R. P. Novo, C. Smith, V. Zapanta, M. Diaz, I. M. Hiatt, T. Hegyi

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

We examined the ventilatory response to inhaled CO2 in 77 infants at postconceptional ages ranging from 31 to 50 wk, 43 of whom were also evaluated with a 12-h pneumocardiogram (PCG). Infants were tested after sedation with chloral hydrate, and monitored with ECG and transcutaneous oxygen and CO2 monitors. Sleep state was evaluated by visual inspection of the infant's behavior. Among the 43 infants examined with the PCG, 22 had abnormal PCGs. Of these, 27% had significantly (p < .05) abnormal CO2 response slopes, compared to 9% of those with normal PCGs. Breathing frequency did not change after CO2 inhalation in 82% of the abnormal PCG and in 33% of the normal PCG groups.

Original languageEnglish (US)
Pages (from-to)873-877
Number of pages5
JournalCritical care medicine
Volume14
Issue number10
DOIs
StatePublished - 1986

All Science Journal Classification (ASJC) codes

  • Critical Care and Intensive Care Medicine

Fingerprint Dive into the research topics of 'Ventilatory responses to carbon dioxide in infants at risk for sudden infant death syndrome'. Together they form a unique fingerprint.

Cite this