Whole-Genome sequences of two Borrelia afzelii and two Borrelia garinii Lyme disease agent isolates

Sherwood R. Casjens; Emmanuel F. Mongodin; Wei Gang Qiu; John J. Dunn; Benjamin J. Luft; Claire M. Fraser-Liggett; Steve E. Schutzer

doi:10.1128/JB.05951-11

Whole-Genome sequences of two Borrelia afzelii and two Borrelia garinii Lyme disease agent isolates

Sherwood R. Casjens, Emmanuel F. Mongodin, Wei Gang Qiu, John J. Dunn, Benjamin J. Luft, Claire M. Fraser-Liggett, Steve E. Schutzer

New Jersey Medical School (NJMS), Medicine, Division of Allergy and Immunology

Research output: Contribution to journal › Comment/debate › peer-review

47 Scopus citations

Abstract

Human Lyme disease is commonly caused by several species of spirochetes in the Borrelia genus. In Eurasia these species are largely Borrelia afzelii, B. garinii, B. burgdorferi, and B. bavariensis sp. nov. Whole-genome sequencing is an excellent tool for investigating and understanding the influence of bacterial diversity on the pathogenesis and etiology of Lyme disease. We report here the whole-genome sequences of four isolates from two of the Borrelia species that cause human Lyme disease, B. afzelii isolates ACA-1 and PKo and B. garinii isolates PBr and Far04.

Original language	English (US)
Pages (from-to)	6995-6996
Number of pages	2
Journal	Journal of bacteriology
Volume	193
Issue number	24
DOIs	https://doi.org/10.1128/JB.05951-11
State	Published - Dec 2011

All Science Journal Classification (ASJC) codes

Microbiology
Molecular Biology

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title = "Whole-Genome sequences of two Borrelia afzelii and two Borrelia garinii Lyme disease agent isolates",

abstract = "Human Lyme disease is commonly caused by several species of spirochetes in the Borrelia genus. In Eurasia these species are largely Borrelia afzelii, B. garinii, B. burgdorferi, and B. bavariensis sp. nov. Whole-genome sequencing is an excellent tool for investigating and understanding the influence of bacterial diversity on the pathogenesis and etiology of Lyme disease. We report here the whole-genome sequences of four isolates from two of the Borrelia species that cause human Lyme disease, B. afzelii isolates ACA-1 and PKo and B. garinii isolates PBr and Far04.",

author = "Casjens, {Sherwood R.} and Mongodin, {Emmanuel F.} and Qiu, {Wei Gang} and Dunn, {John J.} and Luft, {Benjamin J.} and Fraser-Liggett, {Claire M.} and Schutzer, {Steve E.}",

year = "2011",

month = dec,

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language = "English (US)",

volume = "193",

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journal = "Journal of Bacteriology",

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publisher = "American Society for Microbiology",

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Whole-Genome sequences of two Borrelia afzelii and two Borrelia garinii Lyme disease agent isolates. / Casjens, Sherwood R.; Mongodin, Emmanuel F.; Qiu, Wei Gang; Dunn, John J.; Luft, Benjamin J.; Fraser-Liggett, Claire M.; Schutzer, Steve E.

In: Journal of bacteriology, Vol. 193, No. 24, 12.2011, p. 6995-6996.

Research output: Contribution to journal › Comment/debate › peer-review

TY - JOUR

T1 - Whole-Genome sequences of two Borrelia afzelii and two Borrelia garinii Lyme disease agent isolates

AU - Casjens, Sherwood R.

AU - Mongodin, Emmanuel F.

AU - Qiu, Wei Gang

AU - Dunn, John J.

AU - Luft, Benjamin J.

AU - Fraser-Liggett, Claire M.

AU - Schutzer, Steve E.

PY - 2011/12

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N2 - Human Lyme disease is commonly caused by several species of spirochetes in the Borrelia genus. In Eurasia these species are largely Borrelia afzelii, B. garinii, B. burgdorferi, and B. bavariensis sp. nov. Whole-genome sequencing is an excellent tool for investigating and understanding the influence of bacterial diversity on the pathogenesis and etiology of Lyme disease. We report here the whole-genome sequences of four isolates from two of the Borrelia species that cause human Lyme disease, B. afzelii isolates ACA-1 and PKo and B. garinii isolates PBr and Far04.

AB - Human Lyme disease is commonly caused by several species of spirochetes in the Borrelia genus. In Eurasia these species are largely Borrelia afzelii, B. garinii, B. burgdorferi, and B. bavariensis sp. nov. Whole-genome sequencing is an excellent tool for investigating and understanding the influence of bacterial diversity on the pathogenesis and etiology of Lyme disease. We report here the whole-genome sequences of four isolates from two of the Borrelia species that cause human Lyme disease, B. afzelii isolates ACA-1 and PKo and B. garinii isolates PBr and Far04.

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